Magnesium L-threonate

History of Magnesium L-threonate

Magnesium L-threonate is a relatively recent addition to the family of magnesium supplements. Developed by a team of scientists at the Massachusetts Institute of Technology (MIT), this unique compound was specifically designed to increase the brain’s absorption of magnesium.

Traditional forms of magnesium have difficulty crossing the blood-brain barrier, a hurdle that magnesium L-threonate effectively overcomes. Since its inception, this form of magnesium has quickly gained traction in the health and wellness community for its potential neuroprotective benefits.

Scientific Makeup of Magnesium L-Threonate

Magnesium L-threonate is a unique compound in which magnesium is chelated, or bonded, to L-threonic acid, a metabolite of vitamin C. This molecular configuration enhances the absorption of magnesium in the brain, overcoming the limitations of traditional forms of magnesium.

Magnesium L-threonate is the only form of magnesium proven to effectively raise the brain’s magnesium levels, thus optimising neurological health.


Benefits of Magnesium L-Threonate

The benefits of magnesium L-threonate are primarily focused on brain health and cognitive function:

1. Improved Cognitive Abilities: Studies have demonstrated that magnesium L-threonate can enhance synaptic plasticity, which in turn supports improved learning and memory functions.

2. Mood and Sleep Regulation: Magnesium L-threonate may help regulate mood and improve sleep quality due to its influence on neurotransmitters and sleep-regulating hormones.

3. Neuroprotection: It’s suggested that magnesium L-threonate could provide neuroprotective benefits, potentially slowing cognitive decline associated with ageing.

4. Combating Magnesium Deficiency: As it can efficiently cross the blood-brain barrier, it serves as a reliable option for correcting brain magnesium deficiencies.

When combined with a balanced diet and other nutrients like omega-3 fatty acids and B vitamins, magnesium L-threonate can provide comprehensive support for cognitive health.


Safety and Dosages of Magnesium L-Threonate

Magnesium L-threonate is generally well-tolerated and safe for most people. A standard dosage is around 150 -250 mg per day, although this can vary depending on individual needs. As with any supplement, it’s advisable to start with a lower dose and adjust as necessary. Side effects are rare but may include drowsiness and digestive upset. Consult a healthcare provider before beginning any new supplement regimen.

In Europe, regulations pertaining to food supplements such as magnesium are established by the European Food Safety Authority (EFSA). These regulations are aimed at ensuring that supplements are safe for consumers and appropriately labelled. For magnesium in particular, the EFSA has set a maximum daily limit for magnesium in food supplements at 250mg.

Magnesium L-threonate in the UK and Europe

Regulatory bodies, including the UK’s Food Standards Agency (FSA) and the European Food Safety Authority (EFSA), have stringent guidelines to ensure the safety and efficacy of supplements. In line with these guidelines, the sale of Magnesium L-threonate as a supplement has been disallowed in both the UK and Europe.

The reason for this ban is due to insufficient evidence on the safety profile and potential long-term effects of this specific form of magnesium. As a result, at Supplement Factory we comply strictly with these regulations, focusing on the manufacturing and sale of approved magnesium forms that have robust safety profiles and are scientifically validated.

Forms of Consumption

Magnesium L-threonate is most commonly available in capsule or powder form. Both options offer the same benefits, with the best choice often coming down to personal preference. Capsules provide convenience and pre-measured dosage, making them ideal for those on-the-go or preferring not to taste the supplement.

Powders offer versatility, as they can be mixed with water, juice, or blended into smoothies. This option may be preferred by individuals needing higher doses or desiring to fine-tune their intake.

In addition to standalone products, magnesium L-threonate is often included in comprehensive brain health or nootropic supplement formulations, combining it with ingredients such as phosphatidylserine, ginkgo biloba, and other B-vitamins for enhanced benefits.

As a leading provider of contract manufacturing services, Supplement Factory can assist brands in developing a bespoke magnesium L-threonate product, whether in capsule, tablet, or powder form.

To learn more about the potential of magnesium L-threonate in your supplement line, please contact us. Our team of experts are on hand to provide guidance and help you develop high-quality products that meet the needs of your customers.