vitamin A

History of Ingredient

Vitamin A Retinol has an illustrious historical narrative dating back to the early 20th century, when it was first identified as an essential nutrient for vision. Extracted initially from fish liver oils, scientists quickly grasped its multifaceted utility in both human and animal health.

Vitamin A has witnessed a plethora of advancements in terms of its extraction methods, refinement, and categorisation. Over time, its forms have diversified, encompassing variants like retinyl palmitate and retinyl acetate, amongst others.

Scientific Make-Up

Vitamin A Retinol is a fat-soluble vitamin with a molecular formula of C_20H_30O. It is a form of preformed vitamin A, which means it directly imparts the vitamin’s physiological functions without requiring conversion. Retinol belongs to a family of chemical compounds known as retinoids, which also include retinal and retinoic acid.

Its molecular structure consists of a cyclohexenyl ring, a polyene side-chain with four double bonds, and a hydroxyl group, thereby rendering it both stable and bioavailable.


Benefits of Ingredient

Vitamin A Retinol is celebrated for its extensive range of health benefits. Most prominently, it is vital for maintaining good vision, particularly in low-light conditions. Studies suggest that retinol plays an integral role in the formation of the light-absorbing molecule rhodopsin, which is crucial for vision. Moreover, it is indispensable for cell growth and differentiation, thereby supporting skin health and bolstering the immune system.

In recent years, its anti-ageing properties have been widely researched, showing a reduction in fine lines and wrinkles. Its antioxidant capabilities neutralise free radicals, preventing cellular damage. Research on its role in bone health has unveiled promising results, making it a potential synergistic partner to calcium and vitamin D.

Notably, scientific studies corroborate these claims, endorsing vitamin A as a versatile ingredient in supplement formulations. Furthermore, it supports reproductive health and is crucial for embryo development. The extensive applicability of retinol makes it a sought-after ingredient in nutraceuticals, skincare products, and multivitamin formulations.


Forms of Consumption

Vitamin A Retinol is available in a variety of consumption methods tailored to individual needs and preferences. Oral supplements are the most common form and come in capsules, tablets, and liquid forms. Softgels are particularly popular for their higher bioavailability and ease of consumption.

Moreover, topical retinol is a mainstay in skincare products such as serums, creams, and lotions. These are not just advantageous for skin health but also offer targeted delivery for anti-ageing and acne treatment.

Recent innovations include liposomal delivery systems that encapsulate the retinol molecule, thereby increasing its stability and absorption rate. Patches and intramuscular injections are other forms that are generally administered under medical supervision.


Safety + Dosages

While Vitamin A Retinol is generally considered safe, excessive consumption can lead to toxicity. The recommended daily intake for adults is approximately 900 micrograms for men and 700 micrograms for women.

Pregnant women are advised to consult healthcare professionals due to the risk of teratogenic effects. Overdosage symptoms include dizziness, nausea, and even hair loss.

Use and Legality in UK, EU, US, and Globally

In the UK, EU, and US, the sale and consumption of Vitamin A Retinol supplements are generally permitted. In the European Union, it is regulated under the Food Supplements Directive, while in the United States, it falls under the jurisdiction of the FDA. Globally, the World Health Organization endorses the use of Vitamin A for treating deficiency and for prenatal care.

However, regulations vary regarding the maximum permissible dosage in supplements. Companies like Supplement Factory, committed to GMP manufacturing standards, adhere to international laws, ensuring the production of safe and high-quality supplements for various brands. Countries like Japan have stringent regulations requiring specific labeling for retinol-based products.

Supplement Factory can assist your brand in formulating high-quality, compliant Vitamin A Retinol supplements. Turn to experts to achieve the best in supplement excellence. Contact us to learn more.