History of Magnesium

Magnesium, named after the region of Magnesia in Greece where it was first discovered, has a long history of therapeutic use. As an essential mineral, its vital role in human health was recognised early on. By the late 17th century, Epsom salts, otherwise known as magnesium sulphate, were widely used for their laxative properties.

As scientific understanding grew, it was discovered that magnesium plays a pivotal role in over 300 biochemical reactions in the body. In the 20th century, it was further researched for potential health benefits, ranging from cardiovascular health to bone density support.

Scientific Makeup of Magnesium

Magnesium is a mineral, specifically an alkaline earth metal, and is the fourth most abundant mineral in the human body. It plays a vital role in the functioning of the human body, participating in the catalysis of more than 300 enzyme-driven biochemical reactions.

Magnesium contributes to the structural development of bone, DNA synthesis, and is required for the synthesis of glutathione, an important intracellular antioxidant. It aids in the active transport of calcium and potassium ions across cell membranes, which is crucial for nerve impulse conduction, muscle contraction, and normal heart rhythm.


Benefits of Magnesium

Magnesium’s myriad health benefits are well-documented. It plays an integral role in a variety of physiological functions:

1. Bone Health: Magnesium is crucial for bone formation and influences the activities of osteoblasts and osteoclasts, cells responsible for bone health.

2. Heart Health: Studies have shown magnesium is essential for heart health, regulating heart rhythm, and helping to prevent heart disease.

3. Mood and Brain Health: Magnesium’s role in brain function and mood is widely researched. Some evidence suggests it may help mitigate symptoms of depression and anxiety.

4. Digestion and Muscle Health: Magnesium aids digestion by acting as a coenzyme in the digestive tract. It also helps to maintain normal muscle and nerve function.



Safety and Dosages of Magnesium

Magnesium is generally safe for most adults when taken by mouth appropriately or when administered intravenously by a healthcare provider. The recommended daily amount is 400-420 mg for men and 310-320 mg for women.

Excessive doses might cause side effects including nausea, abdominal cramping, and diarrhoea. Certain medications may interact with magnesium, including diuretics, heart medications, and antibiotics. Always consult with a healthcare provider before starting any new supplement regimen.

In Europe, regulations pertaining to food supplements such as magnesium are established by the European Food Safety Authority (EFSA). These regulations are aimed at ensuring that supplements are safe for consumers and appropriately labelled. For magnesium in particular, the EFSA has set a maximum daily limit for magnesium in food supplements at 250mg.

Forms of Consumption

Magnesium supplements are available in various forms, each with distinct benefits, bioavailability, and uses.

1. Magnesium Oxide: This form contains a high amount of elemental magnesium but has lower bioavailability.

2. Magnesium Citrate: Commonly used for its laxative properties, this form has better bioavailability than magnesium oxide.

3. Magnesium Chloride: Used in topical applications, magnesium chloride is also taken orally and offers high bioavailability.

4. Magnesium Glycinate: Known for its high bioavailability and gentleness on the stomach.

5. Magnesium Malate: Fused with malic acid, it’s suggested for those with fatigue and muscle pain.

6. Magnesium Taurate: Combines magnesium with taurine, an amino acid beneficial for cardiovascular health.

7. Magnesium L-Threonate: A newer form linked to improved brain function.

8. Magnesium Sulfate: Also known as Epsom salt, it is commonly used in bath soaks.

As a trusted manufacturer, the Supplement Factory offers a wide range of magnesium supplements to suit various health needs and preferences. We also provide capsule manufacturing and tablet manufacturing services for brands seeking to develop their own magnesium products.

At Supplement Factory, we remain committed to providing high-quality, safe, and effective dietary supplements to support the health and wellbeing of your customers. Please contact us for more information on our magnesium supplements and services.