Vitamin B1 Thiamin

History of Ingredient

Thiamin, more commonly known as Vitamin B1, traces its discovery back to the early 20th century when Dutch physician Christiaan Eijkman identified a substance that could prevent beriberi—a debilitating disease marked by nerve degeneration and muscular weakness.

Subsequent research isolated this essential nutrient, recognising its critical role in carbohydrate metabolism and neural function.

Differences Between Vitamin B1 Thiamin and Vitamin B1 Benfotiamine

Though both Thiamine and Benfotiamine are categorised as Vitamin B1, they differ substantially in their molecular structure, bioavailability, and therapeutic applications. Thiamine is a water-soluble vitamin that has general benefits, such as aiding in the metabolism of carbohydrates and supporting nervous system function. On the other hand, Benfotiamine is a lipid-soluble derivative of thiamine, which allows for enhanced bioavailability.

This critical difference in solubility permits Benfotiamine to be more efficiently absorbed through the intestinal wall and stored within the body. As a result, Benfotiamine is often the choice in clinical situations that require higher levels of thiamine, particularly for conditions like diabetic neuropathy and other nerve-related issues.


Scientific Make-up

Thiamin is a water-soluble vitamin, categorised under the B-complex family. Its chemical structure comprises a pyrimidine and a thiazole ring, connected by a methylene bridge.

The most biologically active form of thiamin is Thiamine Pyrophosphate (TPP), which serves as a vital cofactor in numerous enzymatic reactions. Understanding the biochemical nature of Thiamin allows for its more effective inclusion in multivitamin formulations and other health supplements.


Benefits of Ingredient

Thiamin offers a plethora of health benefits, primarily in the conversion of carbohydrates into energy and the regulation of glucose metabolism. It is essential for the proper functioning of the nervous system, enhancing cognitive ability and reducing stress levels. Additionally, it is instrumental in maintaining a healthy heart, aiding in the proper contraction of muscles and the production of hydrochloric acid in the stomach.

Studies like this one have shown its effectiveness in treating Wernicke-Korsakoff syndrome, a brain disorder primarily linked to alcohol abuse. Thiamin can be paired effectively with other essential nutrients like Magnesium and Vitamin B12 for improved synergistic benefits, which is crucial for comprehensive health solutions.


Forms of Consumption

Thiamin can be consumed through various forms, offering consumers the flexibility to integrate it into their health regimes seamlessly.  Many ready-to-drink beverages are now incorporating Thiamin for immediate absorption. These variations allow Supplement Factory to customise the delivery methods of Thiamin, enabling a tailored nutritional approach for your brand.

For those interested in natural sources, whole grains, meat, and legumes are excellent choices. In addition, Thiamin can also be found in powder supplements and herbal formulations, diversifying its application across an array of health and wellness categories.


Safety + Dosages

Thiamin is generally considered safe for most individuals, with minimal side effects when taken within the recommended dosage. Adult men require approximately 1.2mg per day, whereas women necessitate around 1.1mg daily.

However, overconsumption can result in mild adverse reactions like nausea and irritability. Before beginning any supplement regimen that includes Thiamin, consult with a healthcare provider to determine the most appropriate dosage for your specific needs.


Use and Legality in the UK, EU, US and Globally

Thiamin is widely recognised and permitted for use in dietary supplements and food fortifications across the UK, EU, US and most of the world. Regulatory agencies such as the MHRA in the UK, the FDA in the US, and the EFSA in the EU have set forth guidelines ensuring the safe and effective use of Thiamin.

While it is classified as a food supplement in most jurisdictions, it is always essential to adhere to the local regulatory landscape for proper compliance, particularly when considering the introduction of new formulations.

As the understanding of this crucial nutrient evolves, so too will the opportunities to maximise its efficacy in achieving optimal health. Contact us to learn more.